February 2021

We have previously drawn your attention to published corroborative research that confirms the importance of nucleotides for recovery from infections (such as COVID-19). The web-based magazine ‘What Doctors Don’t Tell You’ (WDDTY) posted an article on their main website and Facebook page recently reporting on Spanish research into the relationship between telomere length and the impact or severity of COVID-19 infections.

One thing in common

“People who suffer badly from a Covid-19 infection have one thing in common—and it’s not their age or having underlying health problems. They all tend to have much shorter telomeres, the caps on the end of DNA strands that have been closely linked to ageing.”

What are telomeres

“Telomeres protect chromosomes in cells, and each time a cell divides, its telomeres shorten until they can no longer protect the cell’s function. Once the damaged cell stops dividing, new tissue is no longer being generated. The result is bodily ageing and health problems such as pulmonary fibrosis when lung tissue starts to stiffen and harden.”

To read the article in full please follow this link

The importance of nucleotide supply to support telomere health

Dr Peter Koeppel has written about the importance of nucleotide supply to support telomeres, cellular health and healthy ageing. We drew your attention to an article Dr Koeppel published in Functional Sports Nutrition magazine (FSN) back in September 2019 reporting on US research that shows the importance of nucleotides to keep cells young.

To download and read the article in full please follow this link 

The paper that this research quotes, is on our database and can be found here

That’s all for this month. Once again, if anyone else has knowledge of anything nucleotide-related that you feel should be mentioned on these pages please don’t hesitate to get in touch via our contact section.

Until then, regards - Gordon
 

February, 2021

This month we have added some very interesting nucleotide-related publications covering a wide range of topics including: Immune Health, Digestive Health, Cold Related Symptoms and Healthy Nutrition.

If anyone has more to add please drop me an email at info(at)nucleotides4health.org 

Thanks once again to everyone who gets in touch, for whatever reason. Interaction and knowledge-sharing was always a big part of the idea behind Nucleotides for Health in the hope that more research and investigation is conducted into the subject. A list of the papers that have recently been added to our database appear below:
 

Gastrointestinal Publications:

Mohamed FF, Hady MM, Kamel NF, Ragaa NM. The impact of exogenous dietary nucleotides in ameliorating Clostridium perfringens infection and improving intestinal barriers gene expression in broiler chicken. Vet Anim Sci. 2020 Jun 25; 10: 100130.

Immunity Publications:

Davidson I., Fyfe L. A randomised double-blind placebo controlled trial of a nucleotide-containing supplement NuCell® on symptoms of participants with the common cold - A pilot study. EC Nutrition 4.1 (2016): 804-811.

Other Publications:

Burnstock G. Purinergic signalling in the reproductive system in health and disease. Purinergic Signalling. 2014 Mar; 10(1): 157-87.

Burnstock G. Purinergic signalling in the gastrointestinal tract and related organs in health and disease. Purinergic Signalling. 2014 Mar; 10(1): 3-50.

Added to the N4H Database 17/02/2021

A full list of papers can be found on our publications pages.
 

That’s all for this update. Once again, if anyone else has knowledge of anything nucleotide-related that you feel should be mentioned on these pages please don’t hesitate to get in touch via our contact section.

Until then, regards - Gordon
 

January 2021

Dr Peter Koeppel contributes to an article in the Jan/Feb 2021 issue of Functional Sports Nutrition (FSN) Magazine (www.fsnmag.com) “Supplements: Why quality Matters” discussing the quality of ingredients used in food supplements. How and why this is so important, especially for nucleotide-based supplements. And the additional importance regarding safety against contamination for sportsmen and women.

The importance of nucleotide supplementation

“There are certain situations in which the quality of a supplement, in terms of nutrient availability, has greater importance, and this is when the body becomes overwhelmed by severe stress, illness or injury. During these times, certain nutrients become conditionally essential.”

“However, when these high challenging situations prevail, the body starts to have trouble creating enough of these nutrients. In such cases, these nutrients enter essential territory – hence, the term ‘conditionally essential’, and dietary sources become of paramount importance.”

Increasing the gut nucleotide pools leads to improved villi repair and maintenance

“Dr Koeppel went on to explain that a positive spin-off from delivering nucleotides in a purified and balanced way through supplementation is increased absorption, which is achieved by the consequential improvement in gut morphology. Increasing the gut nucleotide pools leads to improved villi repair and maintenance processes, and higher levels of bifidobacteria. Not only is the absorption of nutrients supplied via food improved, so are those delivered via other supplements containing other conditionally essential nutrients …”

To download and read the article in full please follow this link 
 

That’s all for this month. Once again, if anyone else has knowledge of anything nucleotide-related that you feel should be mentioned on these pages please don’t hesitate to get in touch via our contact section.

Until then, regards - Gordon
 

January, 2021

This month we have added some very interesting nucleotide-related publications covering a wide range of topics including: Digestive Health, Immune Health, Healthy Nutrition, Exercise Stress and Endurance.

If anyone has more to add please drop me an email at info(at)nucleotides4health.org 

Thanks once again to everyone who gets in touch, for whatever reason. Interaction and knowledge-sharing was always a big part of the idea behind Nucleotides for Health in the hope that more research and investigation is conducted into the subject. A list of the papers that have recently been added to our database appear below:
 

Gastrointestinal Publications:

Lee SI, Kim IH. Nucleotide-mediated SPDEF modulates TFF3-mediated wound healing and intestinal barrier function during the weaning process. Scientific Reports. 2018 Mar 19; 8(1): 4827.

Other Publications:

Leung K-Y, De Castro SCP, Savery D, Copp AJ, Greene NDE. Nucleotide precursors prevent folic acid-resistant neural tube defects in the mouse. Brain. 2013 Sep; 136(9): 2836-2841.

Ostojic SM, Idrizovic K, Stojanovic MD. Sublingual nucleotides prolong run time to exhaustion in young physically active men. Nutrients. 2013 Nov 21; 5(11): 4776-85.

Added to the N4H Database 27/01/2021

A full list of papers can be found on our publications pages.
 

That’s all for this update. Once again, if anyone else has knowledge of anything nucleotide-related that you feel should be mentioned on these pages please don’t hesitate to get in touch via our contact section.

Until then, regards - Gordon
 

October 2020

In an article entitled “An ‘essential’ nutrient?” in the latest on-line edition of “New Food Magazine – the prominent thought leadership platform for the food and beverage industry", Dr Robert Verkerk gives a strong argument for the inclusion of nucleotides in functional foods and beverages.

Dr Robert Verkerk (internationally acclaimed, multi-disciplinary sustainability scientist with a 35-year background in environmental, agricultural, food, nutritional and health sciences) ponders if our immune systems are up to today’s modern challenges without some supplemental “support”.

Primordial, not novel

“Nucleotides are an emerging group of ingredients that hold great potential for improving the modulation of the fantastically complex human immune system. There is nothing new about nucleotides themselves: they were likely among the chemical compounds that helped kick-start life in the ‘primordial soup’ over four billion years ago.”

Conditionally essential

“The fundamental importance of nucleotides in growth, development and immune health in humans, means nucleotides are widely recognised as ‘conditionally essential’ nutrients.”

In conclusion

“In a world in which our immune systems, gut and bodily repair systems require all the help they can get, inclusion of balanced nucleotides in functional foods and beverages is an emerging opportunity offering significant benefits to consumers.”

To read the article in full please follow this link 
 

That’s all for this month. Once again, if anyone else has knowledge of anything nucleotide-related that you feel should be mentioned on these pages please don’t hesitate to get in touch via our contact section.

Until then, regards - Gordon
 

October, 2020

This month we have added some very interesting nucleotide-related publications covering a wide range of topics including: Improved Immune Response, Digestive Health, Healthy Nutrition and Developmental Effects.

If anyone has more to add please drop me an email at info(at)nucleotides4health.org 

Thanks once again to everyone who gets in touch, for whatever reason. Interaction and knowledge-sharing was always a big part of the idea behind Nucleotides for Health in the hope that more research and investigation is conducted into the subject. A list of the papers that have recently been added to our database appear below:
 

Gastrointestinal Publications:

Che L, et al. Dietary Nucleotides Supplementation Improves the Intestinal Development and Immune Function of Neonates with Intra-Uterine Growth Restriction in a Pig Model. PLoS One. 2016 Jun 15; 11(6): e0157314.

Immunity Publications:

Riera et al. Dietary nucleotide improves markers of immune response to strenuous exercise under a cold environment. Journal of the International Society of Sports Nutrition 2013, 10:20.

Other Publications:

Xu M, Ma Y, Xu L, Xu Y, Li Y. Developmental effects of dietary nucleotides in second-generation weaned rats. J Med Food. 2013 Dec; 16(12): 1146-52.

Added to the N4H Database 07/10/2020

A full list of papers can be found on our publications pages.
 

That’s all for this update. Once again, if anyone else has knowledge of anything nucleotide-related that you feel should be mentioned on these pages please don’t hesitate to get in touch via our contact section.

Until then, regards - Gordon