Nucleotide News

This area of our website is for those visitors who want to keep up-to-date with all the latest nucleotide related developments. Including news on the latest scientific papers and research publications as they are released it will also keep you in the know about worldwide events, exhibitions and seminars relating to the world of Nucleotides.

For returning visitors this section acts as a very handy overview of the updates and new additions to our site, To make sure you don’t miss a thing!

We are always on the lookout to keep the site up-to-date but we cannot be aware of everything that’s out there so we also rely heavily on your help to point us in the right direction.

If anyone knows of any papers or published works that they think deserve inclusion in our collection please get in touch. Submit the link for approval via the contact area of our site and we'll give you a mention here.


In-depth nucleotide article in latest "NHD" magazine

Aug/Sept 2011

Nucleotides — speculation on lifestyle-induced essentiality

In the latest issue of "NHD" –  The Dietitians' Magazine (NHDmag.com) – Dr Robert Verkerk discusses the fact that nucleotides – considered by researchers in the field as only 'conditionally essential' until now – may actually be 'seminally important for good health' and takes us on a journey through some of the main landmarks in the story of discovery that leads to this powerful speculation.

Scientists are now speculating that there is a dietary and lifestyle-induced essentiality for nucleotides:

"There is now widespread recognition among scientists that dietary simplification associated with the industrialisation of the human food supply is contributing to increased incidence of preventable chronic, inflammatory diseases, which now place the greatest burden on healthcare systems the world over."

Dr Robert Verkerk and Dr Peter Koeppel conclude:

"We therefore speculate: Could it be that fundamental nutritional benefits associated with nucleotides, such as DNA repair, cancer risk reduction, and gastrointestinal and immune health, would be well served by consistently elevated intake of those invaluable DNA spare parts that appear to be otherwise in short supply? We propose that this requirement for supplementary nucleotides could be contemplated as a form of lifestyle-induced essentiality, as distinct from the more usually considered physiological essentiality."

To download and read the article in full please follow this link 

 

That’s all for this month. Once again, if anyone else has knowledge of anything nucleotide-related that you feel should be mentioned on these pages please don’t hesitate to get in touch via our contact section.

Until then, regards - Gordon


New Additions to the Site

November, 2012

This month we have added some very interesting nucleotide-related publications covering a wide range of topics including: Cancer, Infants, Memory, Sexual performance, Healthy Nutrition, Intestinal Health and Immunity.

If anyone has more to add please drop me an email on gnelson(at)nucleotides4health.org .

Thanks again to everyone who gets in touch, for whatever reason. Interaction and knowledge-sharing was always a big part of the idea behind Nucleotides for Health in the hope that more research and investigation is conducted into the subject. A list of the papers that have been added recently appear below:

 

Gastrointestinal Publications:

Bustamante SA, Sanches N, Crosier J, Miranda D, Andmark GC, Miller JS. Dietary Nucleotides: Effects on the Gastrointestinal System in Swine. J Nutr. 1994 Jan;124(1 Suppl):149S-156S.

 

Immunity Publications:

Jyonouchi H. Nucleotide actions on humoral immune responses. J Nutr. 1994 Jan;124(1 Suppl):138S-143S.

Vitiello L, Gorini S, Rosano G, la Sala A. Immunoregulation through extracellular, ATP (eATP), nucleotides. Blood. 2012 Jun 1.

 

Nutritional Publications:

Clayton P, Rowbotham J. How the Mid-Victorians Worked, Ate and Died. Int J Environ Res Public Health. 2009 March; 6(3): 1235–1253.

Rudolph FB. The biochemistry and physiology of nucleotides. J Nutr. 1994 Jan;124(1 Suppl):124S-127S.

Uauy R. Non-immune system responses to dietary nucleotides. J Nutr. 1994 Jan;124(1 Suppl):157S-159S.

 

Other Publications:

Bester AC, Roniger M, Oren YS, Im MM, Sarni D, Chaoat M, Bensimon A, Zamir G, Shewach DS, Kerem B. Nucleotide deficiency promotes genomic instability in early stages of cancer development. Cell. 2011 Apr 29;145(3):435-46.

Chen TH et al. Effects of dietary nucleoside-nucleotide mixture on memory in aged and young memory deficient mice. Life Sci. 1996;59(21):PL325-30.

Chen TH et al. A Nucleoside-Nucleotide Mixture May Reduce Memory Deterioration in Old Senescence-Accelerated Mice. J Nutr. 2000;130:3085-3089.

Hupertan V, Neuzillet Y, Stücker O, Pons C, Leammel E, Lebrett T. Effects of nucleotides adenosine monophosphate and adenosine triphosphate in combination with L-arginine on male rabbit corpus cavernosum tissue. International Journal of Andrology. doi: 10.1111/j.1365-2605.2012.01290.

Sánchez CL, Cubero J, Sánchez J, Chanclón B, Rivero M, Rodríguez AB, Barriga C. The possible role of human milk nucleotides as sleep inducers. Nutr Neurosci. 2009 Feb;12(1):2-8.

Yamamoto S, Wang MF, Adjei AA, Ameho CK. Role of nucleosides and nucleotides in the immune system, gut reparation after injury, and brain function. Nutrition. 1997 Apr;13(4):372-4.

Added to the N4H Database 25/11/2012

A full list of papers can be found on our publications pages.

That’s all for this update. Once again, if anyone else has knowledge of anything nucleotide-related that you feel should be mentioned on these pages please don’t hesitate to get in touch via our contact section.

Until then, regards - Gordon


Nucleotides article in latest "Functional Sports Nutrition" magazine

July 2011

In the latest issue of "Functional Sports Nutrition" –  The magazine for personal trainers and sports professionals serious about sports nutrition (www.fsnmag.com) – Dr Peter Koeppel discusses the role of nucleotides in health and specifically in relation to immunity, recovery and improved response for athletes:

Nucleotides and immunity

"If the nucleotide supply is insufficient, the ’flu viruses will proliferate unhindered, which may lead to more severe symptoms and prolonged illness. Conversely, with enough nucleotides the infection can be quickly counteracted during its initial stages."

"Importantly, nucleotides do not stimulate innate or acquired immunity, but rather provide the resource for unhindered cell proliferation, gene expression, and response to special environmental and physical challenges. Their universal use and fundamental functionality and efficacy in every living organism make nucleotides a valuable management tool for many stress- and health-related conditions."

Dietary and supplemental nucleotides

"The problem is that foods rich in nucleotides are now rarely on our menu. Meat products from organs such as liver, kidney, intestines and lung are particularly rich sources of nucleotides, but are now rarely eaten."

Nucleotides for athletes: improved recovery and muscle-to-fat ratio

"Futhermore, the more quickly cells are resynthesised after workouts, the faster and better will be the recovery."

"Particularly, in phases of intensive training, an additional supply of nucleotides through dietary intake is important. Nucleotides are essential for muscle function in different ways: besides protein synthesis, they improve oxygen transport and reduce the effects of lesions in the intestinal tract and muscles." 

To download and read the article in full please follow this link 

 

That’s all for this month. Once again, if anyone else has knowledge of anything nucleotide-related that you feel should be mentioned on these pages please don’t hesitate to get in touch via our contact section.

Until then, regards - Gordon